Atrophic acne scars
Conditions
Interventions
Monotherapy side (Group A):Microneedle Fractional Radiofrequency
Combined side(Group B):MFR combined with Polycaprolactone Microsphere Delivery
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with moderate or more severe atrophic acne scars (ECCA score = 60 points); 2. Age = 18 years, no gender limitation; 3. History of acne scars = 1 year; 4. Willing to participate in this trial, willing to complete subsequent follow-ups, and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant women or those planning to become pregnant. 2. Patients allergic to polycaprolactone, surface disinfectants, or lidocaine anesthetic cream. 3. Patients with facial wounds or skin ulcers. Patients with severe organic or mental diseases. 4. Patients currently participating in other clinical trials. 5. Patients who have undergone laser or energy treatments, cosmetic surgery (such as fillers, injections, plastic surgery), and/or chemical peel treatments in the past year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Echelle d' Evaluation Clinique des Cicatrices d' acne,ECCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety evaluation;Skin thickness;Dermal volume;Pain VAS;Global Aesthetic Improvement Scale,GAIS;VISIA index;Echelle d' Evaluation Clinique des Cicatrices d' acne,ECCA; | — |
Countries
China
Contacts
Public ContactWANG Danru
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed