Clear Cell Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus
Conditions
Interventions
Gold Standard:Assessment of IVC Wall Invasion: Histopathological confirmation of tumor invasion into the inferior vena cava wall
Criteria for Rapid Thrombus Growth: The cranial extension of the tumor
Index test:Multimodal Evaluation System for Clear Cell Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus
Sponsors
The First Medical Center of the General Hospital of the People's Liberation Army of China
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age > 18 years. 2. Histologically confirmed clear cell renal cell carcinoma. 3. Voluntary participation with signed written informed consent.
Exclusion criteria
Exclusion criteria: 1. Presence of absolute contraindications to magnetic resonance imaging (MRI). 2. Severe artifacts on MRI images rendering them non-diagnostic. 3. Postoperative histopathological confirmation of any diagnosis other than clear cell renal cell carcinoma (ccRCC). 4. For retrospective cases: failure to complete multiparametric MRI (mpMRI) within 2 weeks prior to surgery, or received prior neoadjuvant therapy. 5. Received targeted therapy or immunotherapy at baseline, or presence of distant metastasis. 6. Concurrent with other malignancies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the receiver operating characteristic curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Accuracy; | — |
Countries
China
Contacts
Public ContactHaiyi Wang
The First Medical Center of the General Hospital of the People's Liberation Army of China
Outcome results
None listed