Sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria for the SIC Patient Case Group:?? 1. Age >= 18 years; 2. Underwent CRRT for a duration of >= 12 hours; 3. Received blood purification therapy using the Jafron DX-10 system with its matching tubing set and the Fresenius AV1000s filter; 4. Normal function of the blood purification circuit (able to aspirate 20 ml of blood from both lumens within 6 seconds); 5. Experienced unplanned discontinuation of therapy (i.e., total CRRT treatment time = 24 hours) during their CRRT treatment.
Exclusion criteria
Exclusion criteria: ?Exclusion Criteria:?? 1. Patients who were discharged automatically (against medical advice) or died during the treatment; 2.Treatment termination due to non-extracorporeal circuit coagulation reasons, such as patient resuscitation or equipment failure; 3.Patients undergoing hemoperfusion, plasma exchange, artificial liver blood purification, or various combined therapies. ??The exclusion criteria for the control group were the same as those for the case group.??
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coagulation Status Pre-filter Pressure;Pre-filter Pressure;Duration of continuous renal replacement therapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activated partial thromboplastin time;Red blood cell count;Age; | — |
Countries
China
Contacts
Qingdao Municipal Hospital??