Chronic Heart Failure (CHF)
Conditions
Interventions
Experimental Group:based on the combined assessment results of cardiopulmonary exercise testing (CPET) and non-invasive cardiac output monitoring
Control Group :Formulate cardiac rehabilitation programs using cardiopulmonary exercise testing (CPET) assessment
Sponsors
Emergency General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years; 2. Meeting the diagnostic criteria specified in ; 3. NYHA functional classification Class II-III; 4. Left ventricular ejection fraction (LVEF) >= 40%; 5. Stable condition (no acute episode of heart failure within the past 1 month); 6. Exercise rehabilitation training deemed acceptable based on physical fitness assessment, with written informed consent obtained from the patient and their family members.
Exclusion criteria
Exclusion criteria: 1. Acute myocardial infarction (within 1 week) and unstable angina pectoris; 2. Severe arrhythmias (ventricular tachycardia, atrial fibrillation with rapid ventricular response) and acute heart failure exacerbation; 3. Sustained blood pressure > 180/110 mmHg; 4. Severe anemia (Hb < 90 g/L) and uncorrected electrolyte disturbances; 5. Severe pulmonary disease (FEV1 < 50% of predicted value); 6. Cognitive impairment leading to inability to cooperate with rehabilitation training; 7. Cancer patients with an expected survival time of < 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parameters measured by non-invasive cardiac output monitoring (ICG): CO, CI, SV, SVR, ICON;Parameters measured by cardiopulmonary exercise testing (CPET): VO?peak, AT, VE/VCO?, etc.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Parameters measured by echocardiography: LVEF, LAD, LVEDD, LVESD;Parameters measured by the 6 Minute Walk Test (6MWT): 6MWD, Mets, HRmax;Incidence of adverse events: abnormal hypertension, heart failure readmission, angina pectoris, myocardial infarction, etc.;Improvement rate of quality of life: Minnesota Living with Heart Failure Questionnaire (MLHFQ);New York Heart Association (NYHA) functional classification ?; | — |
Countries
China
Contacts
Public ContactZhang Qi
Emergency General Hospital
Outcome results
None listed