Intrauterine space-occupying lesion
Conditions
Interventions
Adult group (18–60 years):Different concentrations of Taigilidine injection
Elderly group (>=60 years):Different concentrations of Taigilidine injection
Sponsors
Fudan University Zhongshan Hospital Xiamen Branch
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. 18 years <= age <= 75 years; 2. Patients scheduled for elective hysteroscopic examination and surgery; 3. American Society of Anesthesiologists (ASA) physical status I–III; 4. Voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe vital organ dysfunction (including second-degree or higher atrioventricular block without a pacemaker, left ventricular ejection fraction 28 kg/m² or < 18 kg/m², or a total body weight < 40 kg. 3 Patients with a history of vaginal delivery or who have undergone cervical dilation within the past 6 months. 4. Patients with a known allergy to any of the study drugs. 5. Patients who are long-term users of sedatives, analgesics, or drugs that may affect opioid metabolism, or who have taken such drugs within 7 days. 6. Patients unable to cooperate with postoperative follow-up or those with communication difficulties. 7. Pregnant or breastfeeding women. 8. Patients with a Mallampati score of III or IV. 9. Patients for whom an adequate medical history cannot be obtained. 10. Patients who refuse to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective Dose (ED) of Taigilidine for Cervical Dilation Response Suppression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of AEs;Patient satisfaction; pain score;Incidence of nausea and vomiting; | — |
Countries
China
Contacts
Public ContactYuejiao Song
Fudan University Zhongshan Hospital Xiamen Branch
Outcome results
None listed