Preoperative pain in elderly patients with hip fractures
Conditions
Interventions
Phase 1: Concentration Exploration Group:Phase 1: Liposomal Bupivacaine (Concentration Sequential)
Phase 2: Volume Exploration Group:Phase 2: Liposomal Bupivacaine (Volume Sequential)
Sponsors
Shunde Hospital of Guangzhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age = 65 years old; 2.Diagnosed as hip fracture (femoral neck fracture, intertrochanteric fracture, intertrochanteric fracture); 3.American Society of Anesthesiologists (ASA) Grades I-III; 4.Resting VAS score = 4 points upon admission; 5.18kg/m2=BMI=30kg/m2; 6.Voluntary signing of informed consent form;
Exclusion criteria
Exclusion criteria: 1.Allergic to liposomal bupivacaine; 2.There is coagulation dysfunction present; 3.Infection at the puncture site; 4.Unable to cooperate with assessment due to mental illness or cognitive impairment; 5.Combined with severe organ dysfunction in the heart, lungs, liver, kidneys, and other organs; 6.Cognitive impairment (Montreal Cognitive Assessment Scale MoCA score<26 points, if education years = 12 years, an additional point will be added for evaluation);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite Success Endpoint; | — |
Secondary
| Measure | Time frame |
|---|---|
| Opioid Rescue Consumption;the dynamic pain scores;Adverse Event Rate;the static pain scores; | — |
Countries
China
Contacts
Public ContactHaobin Peng
Shunde Hospital of Guangzhou University of Traditional Chinese Medicine
Outcome results
None listed