Gingival Recession
Conditions
Interventions
control group:Coronally advanced flap surgery + autogenous subepithelial connective tissue graft
experimental group:Coronally advanced flap surgery + VCMX
Sponsors
Peking University Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.The patient has good compliance and oral hygiene status (full-mouth plaque index = 25% after initial therapy). Age > 18 years old and < 60 years old. 2.There is at least one tooth in the anterior and premolar regions with Grade 1 gingival recession (RT1) caused by non-inflammatory factors, such as traumatic brushing habits, stable period after orthodontic treatment, etc. The depth of gingival recession is = 2mm, accompanied by irritation sensitivity symptoms or aesthetic concerns. 3.The cementoenamel junction (CEJ) can be clearly identified, or there are distinct margins of restorations/fillings. 4.The width of keratinized gingiva apical to the gingival recession is = 1mm.
Exclusion criteria
Exclusion criteria: 1. Poorly controlled systemic diseases (e.g., diabetes mellitus with glycosylated hemoglobin > 7%; hypertension with uncontrolled blood pressure = 160/100 mmHg; ischemic heart disease with unstable angina or myocardial infarction symptoms within 30 days; cardiac arrhythmia such as high-degree atrioventricular block; symptomatic heart failure; infective endocarditis, valvular heart disease, etc.); 2. Smoking. 3. Pregnant or lactating women. 4. Poor oral hygiene control with full-mouth plaque score (FMPS) > 20%. 5. Presence of uncorrected harmful brushing habits that may cause gingival trauma. 6. Untreated periodontitis. 7. Significant malocclusion, crowding, displacement, or overeruption of teeth. 8. Previous periodontal plastic surgery at the target tooth sites. 9. Taking medications that may affect mucosal healing or stimulate gingival hyperplasia (e.g., steroids, calcium channel blockers, antiepileptic drugs, immunological antagonists, etc.). 10. History of head and neck radiotherapy or chemotherapy. 11. Long-term residence in other places or frequent business trips, resulting in inability to return for follow-up visits on schedule.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean root coverage, MRC; | — |
Secondary
| Measure | Time frame |
|---|---|
| keratinized gingiva width, KGW;VAS (Visual Analogue Scale) for aesthetic satisfaction;complete root coverage, CRC;clinical attachment level, CAL;VAS (Visual Analogue Scale) for edema, bleeding, and pain at 1 week postoperatively;recession depth, RD;probing depth, PD;Postoperative Mean Root Coverage Area and Gingival Contour Changes:;recession width, RW;Gingival Thickness Changes; | — |
Countries
China
Contacts
Public ContactYang Gang
Peking University Hospital of Stomatology
Outcome results
None listed