Acute stress disorder
Conditions
Interventions
control group:Administer 0.9% physiological saline solution of equal volume to the dexmedetomidine group via nasal route
Dexmedetomidine group:Administer 1 µ g/kg dexmedetomidine via nasal route
Sponsors
Luzhou Maternal and Child Health Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meets the indications for emergency cesarean section; 2. Clear consciousness, basic communication and understanding skills, able to cooperate in completing psychological scale assessments; 3. Can clearly understand the content of this study, voluntarily participate and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous diagnosis of depression, anxiety disorder or other mental disorders; 2. Long term use of sedatives, antidepressants, or anti anxiety drugs in the past; 3. Known to be allergic to dexmedetomidine or have contraindications for use, such as severe sinus bradycardia, atrioventricular block, etc; 4. Patients with severe heart, liver, and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative acute stress disorder; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate at different time points during surgery;Mean arterial pressure at different time points during surgery;Pulse oximetry at different time points during surgery;Edinburgh Postnatal Depression Scale Score;Pittsburgh Sleep Quality Index Score;Cortisol levels in serum;Norepinephrine levels in serum;Level of malondialdehyde in serum;Serum superoxide dismutase levels; | — |
Countries
China
Contacts
Public ContactWei Luo
Luzhou Maternal and Child Health Hospital
Outcome results
None listed