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Evaluation of phacoemulsification efficiency and visual effects of Clareon PanOptix Pro using Unity VCS combined with 4D phacoemulsification technology in LOCS III 3+cataract: a prospective study

Evaluation of phacoemulsification efficiency and visual effects of Clareon PanOptix Pro using Unity VCS combined with 4D phacoemulsification technology in LOCS III 3+cataract: a prospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122146
Enrollment
Unknown
Registered
2026-04-09
Start date
2026-04-10
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cataract

Interventions

Experimental group:All patients underwent binocular phacoemulsification surgery using Unity VCS with 4D phacoemulsification technology, with Clareon PanOptix Pro trifocal intraocular lens implanted du

Sponsors

Hainan Optometry and Ophthalmology Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age between 45 and 80 years old. 2. At least 40% of age-related cataract patients with LOCS III grade >= 3 in one eye are planning to undergo cataract surgery and have both eyes implanted with Clareon PanOptix Pro intraocular lens/Clareon PanOptix Pro astigmatism correcting intraocular lens or Clareon single focus/Clareon astigmatism correcting intraocular lens (maximum 40% of patients), with the goal of developing an emmetropic eye. 3. For eyes with preoperative regular corneal astigmatism= 0.75D and suitable for implantation of Clareon PanOptix astigmatism correction/Clareon single focus astigmatism correction T3-T6 intraocular lenses, Clareon PanOptix Pro astigmatism correction/Clareon single focus astigmatism correction intraocular lenses will be implanted. According to the Barrett astigmatism calculator, the predicted residual astigmatism should be <= 0.50D. 5. The researchers determined that the potential postoperative visual acuity of each eye could reach 20/25 or better. 6. I have signed the informed consent form for research participation and agree to comply with all research procedures. 7. Able to understand and sign informed consent forms approved by the ethics committee. 8. Willing and able to participate in all planned research visits as required by the plan.

Exclusion criteria

Exclusion criteria: 1. There are any systemic diseases or eye conditions (such as amblyopia, glaucoma, corneal disease, uveitis, macular degeneration or retinopathy, neuro ophthalmic diseases, etc.) that are expected to affect surgical efficiency or potential postoperative vision, irregular astigmatism, iris abnormalities, suspensory ligament instability, polar cataracts, or other conditions that researchers believe should be excluded. 2. Patients planning to undergo femtosecond laser assisted cataract surgery (FLACS). 3. Patients with any history of eye surgery, eye trauma, eye inflammation, or laser treatment (such as fundus laser photocoagulation). 4. Patients who experience intraoperative or postoperative complications.

Design outcomes

Primary

MeasureTime frame
Accumulated dissipated energy (CDE) (intraoperative);Best corrected distance vision defocus curve for both eyes 3 months after surgery;

Secondary

MeasureTime frame
Energy dissipated within the eye (J);ultrasound time;

Countries

China

Contacts

Public ContactChen Wei

Hainan Optometry and Ophthalmology Hospital

chenweimd@wmu.edu.cn+86 137 5772 8118

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026