Anxiety Disorder
Conditions
Interventions
Box Breathing Group:Participants completed a resting-state assessment and a mental arithmetic task in the hospital, followed by one session of box breathing training, with simultaneous multimodal phys
Diaphragmatic Breathing Group:Participants completed a resting-state assessment and a mental arithmetic task in the hospital, followed by one session of diaphragmatic breathing training, with simultan
Natural Breathing Group:Participants completed a resting-state assessment and a mental arithmetic task in the hospital, followed by one session of natural breathing training, with simultaneous multimo
4-7-8 Breathing Group:Participants completed a resting-state assessment and a mental arithmetic task in the hospital, followed by one session of 4-7-8 breathing training, with simultaneous multimodal
Cyclic Hyperventilation Breathing Group:Participants completed a resting-state assessment and a mental arithmetic task in the hospital, followed by one session of cyclic hyperventilation breathing tra
Cyclic Sighing Breathing Group:Participants completed a resting-state assess
Sponsors
Hangzhou Seventh People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age 18–65 years inclusive, both sexes; 2. Meets DSM-5 criteria for anxiety disorder; 3. Hamilton Anxiety Rating Scale (HAMA) score =14 and Hamilton Depression Rating Scale (HAMD-17) score <17; 4. Educational attainment at elementary school level or above, with sufficient comprehension to understand the study content and cooperate throughout the experimental process; 5. Voluntary participation in this study and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with organic brain disorders, neurological disorders, respiratory disorders, cardiovascular disorders, or severe physical illnesses; 2. Individuals with other mental disorders meeting DSM-5 diagnostic criteria, such as developmental disorders, schizophrenia spectrum and other psychotic disorders, bipolar and related disorders, obsessive-compulsive and related disorders, trauma- and stressor-related disorders, somatic symptom and related disorders, disruptive, impulse-control, and conduct disorders, substance-related and addictive disorders, and personality disorders; 3. Individuals who are uncooperative with testing or unable to complete it effectively; 4. Female patients who are pregnant or breastfeeding; 5. Subjects with implanted pacemakers or other medical devices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Scale, HAMA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale-17, HAMD-17;Generalized Anxiety Disorder-7, GAD-7;Patient Health Questionnaire-9 items, PHQ-9;State-trait anxiety inventory, STAI;Panic Disorder Severity Scale, PDSS;Respiratory Symptom Questionnaire;Anxiety Sensitivity Index, ASl;Social Interaction Anxiety Scale, SIAS;Near-Infrared Brain Functional Imaging;Heart rate;Heart Rate Variability;Respiratory rate;Tidal volume;skin conductance;Skin temperature; | — |
Countries
China
Contacts
Public ContactDeng Wei
Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine
Outcome results
None listed