Coronary Heart Disease
Conditions
Interventions
Healthy control group:None
Control group:Basic medical therapy + health education
Intervention group :Basic medical therapy + health education + enhanced external counterpulsation (EECP) treatment
Sponsors
Suzhou Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with Coronary Heart Disease (CHD): 1.Aged 18–80 years; 2.NYHA functional class I–III; 3.Meet the CHD diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Stable Coronary Heart Disease; 4.Meet the indications for 6-minute walk test, cardiopulmonary exercise test, electroencephalogram (EEG), and enhanced external counterpulsation (EECP); 5.Understand the purpose of the clinical trial, participate voluntarily, and provide written informed consent. Healthy Subjects: 1.Aged 18–80 years; 2.No history of major physical diseases, such as severe cardiovascular and cerebrovascular diseases, hepatic or renal insufficiency, or malignant tumors; 3.No history of mental disorders, such as schizophrenia, bipolar disorder, major depressive disorder, etc.; 4.No history of neurological diseases, such as epilepsy, traumatic brain injury, encephalitis, etc.; 5.No history of drug abuse or alcohol dependence; 6.Montreal Cognitive Assessment (MoCA) score = 26; 7.Pittsburgh Sleep Quality Index (PSQI) total score = 7; 8.Provide written informed consent and voluntarily cooperate with quantitative electroencephalogram (qEEG) assessment.
Exclusion criteria
Exclusion criteria: Patients with Coronary Heart Disease (CHD): 1. Pregnant or lactating women; 2. Acute myocardial infarction occurred within 1 month; 3. Those who have received enhanced external counterpulsation (EECP) treatment in the past; 4. Those who are participating in other clinical trials at the same time; 5. Those who have undergone any surgical treatment within 1 month before enrollment; 6. Those with cardiac insufficiency not caused by coronary heart disease or severe aortic stenosis; 7. Those who meet the contraindications for 6-minute walk test, cardiopulmonary exercise test, electroencephalogram (EEG) and EECP. Healthy Subjects: 1. Pregnant or lactating women; 2. Those with a history of head trauma accompanied by loss of consciousness; 3. Those with contraindications to EEG examination (such as scalp infection, skull defect, etc.); 4. Those who are participating in other clinical trials at the same time; 5. Those who have suffered from acute infectious diseases within the recent 1 month; 6. Those who have taken drugs that may affect EEG results (such as sedative-hypnotics, antiepileptic drugs, etc.) within the recent 1 week; 7. Those who cannot cooperate to complete the EEG examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-Minute Walk Distance;Left Ventricular Ejection Fraction;sleep quality;emotional state;Incidence of adverse events;Readmission rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Power Spectral Density;Oxygenated Hemoglobin and Deoxygenated Hemoglobin in the Cerebral Cortex;VO2max;Seattle Angina Questionnaire;NYHA;Quality of Life; | — |
Countries
People's Republic of China
Contacts
Public ContactZhaodi Wang
Suzhou Municipal Hospital
Outcome results
None listed