Nerve block puncture pain
Conditions
Interventions
Oliceridine Group:Intravenous administration of oliceridine at a dose of 0.02 mg/kg prior to the nerve block procedure.
Sufentanil Group:Intravenous administration of sufentanil at a dose of 0.1 mcg/kg prior to the nerve block procedure.
Sponsors
Lu'an People's Hospital of Anhui Province
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: Age >= 65 years, American Society of Anesthesiologists (ASA) classification I-III, body mass index (BMI) 18-30 kg/m^2, resting pain visual analog scale (VAS) score <=3; Elective laparoscopic cholecystectomy; Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Individuals with allergies to oliceridine, sufentanil, or ropivacaine; (2) Individuals with coagulation abnormalities or local infection at the puncture site; (3) Individuals with cognitive, hearing, or language impairments, a history of mental illness, or difficulties in communication and cooperation; (4) Individuals with severe cardiocerebrovascular diseases or hepatic/renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of opioid-induced respiratory depression;visual analogue scale (VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic parameters (MAP, HR, SpO2);Incidence of adverse events;Satisfaction Rating; | — |
Countries
China
Contacts
Public ContactCheng Feng
Lu'an People's Hospital of Anhui Province
Outcome results
None listed