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Study on the Mechanism by which Gastric Cancer Cells Remodel the Immune Microenvironment within Lymph Nodes by Regulating B Cell Germinal Center Activity

Study on the Mechanism by which Gastric Cancer Cells Remodel the Immune Microenvironment within Lymph Nodes by Regulating B Cell Germinal Center Activity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600122095
Enrollment
Unknown
Registered
2026-04-09
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer

Interventions

Observation group:None

Sponsors

Fudan University Affiliated Huashan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age 50-70 years, with no known severe organic diseases. 2. Pathologically confirmed malignant gastric tumor, regardless of gender. 3. Postoperative pathology confirms lymph node metastasis.

Exclusion criteria

Exclusion criteria: 1. Those with difficulty swallowing or symptoms of upper gastrointestinal bleeding; 2. Those with esophageal-gastric varices or esophageal strictures; 3. Those with a history of gastric surgery; 4. Those with coagulation disorders or who need to continuously take anticoagulant or antiplatelet drugs; 5. Those who have contraindications for gastroscopy and mucosal biopsy; 6. Individuals who refuse to cooperate with the research protocol and refuse to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
lymph node;SEMA4G expression level;—

Countries

China

Contacts

Public ContactChengen Hu

Fudan University Affiliated Huashan Hospital

stevenhu76@hotmail.com+86 176 6045 2010

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026