Intervertebral disc degeneration
Conditions
Interventions
Paravertebral myositis + intervertebral disc degeneration group:None
Control Group:None
Sponsors
Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria for both paraspinal muscle degeneration and intervertebral disc degeneration. (2) Aged 18–70 years. (3) Single-level L4/L5 lumbar disc herniation confirmed by MRI and CT, with radiological findings consistent with the clinical manifestations, including low back pain and sciatica. (4) Failure of conservative treatment, with surgical intervention indicated. (5) Provision of written informed consent.
Exclusion criteria
Exclusion criteria: (1) Low back pain attributable to tumors, infection, metabolic disorders, rheumatic or immune diseases. (2) Presence of spinal deformities, including spondylolisthesis, spondylolysis, or scoliosis. (3) A history of lumbar spinal surgery. (4) Concomitant neurological disorders, including amyotrophic lateral sclerosis, Guillain–Barré syndrome, or myasthenia gravis. (5) Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum;Cross-sectional area of the paraspinal muscles; | — |
Countries
China
Contacts
Public ContactZhang Yafeng; Zhao Xuequan
Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine
Outcome results
None listed