Thyroid Cancer
Conditions
Interventions
Experimental group:Using near-infrared fluorescence detection equipment to assist in the identification of parathyroid glands during thyroid cancer surgery
Control group:Surgeon's visual assessment and identification
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged between 18 and 70 years;(2) Differentiated thyroid carcinoma;(3) Underwent total thyroidectomy plus bilateral central lymph node dissection (level VI). Lateral neck lymph node dissection (levels II, III, IV and V) was performed only if FNAB confirmed metastasis.
Exclusion criteria
Exclusion criteria: (1) History of neck surgery, including surgery on the esophagus, thyroid, parathyroid glands (PG), and larynx;(2) Preoperative evaluation showing abnormal morphology or function of the parathyroid glands (PG); (3) Refusal to participate in this study;(4) Patients undergoing endoscopic thyroid surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preoperative serum calcium level;Preoperative parathyroid hormone (PTH) level;Number of identified parathyroid glands (PGs) intraoperatively;Number of suspicious parathyroid glands intraoperatively;Stage of identified PGs or suspicious PGs intraoperatively;Number of autotransplanted PGs;Stage at which autotransplanted PGs were identified;Number of PGs found on pathological histologic examination;Corrected serum calcium level on postoperative day 1;Parathyroid hormone level on postoperative day 1 ;Duration of hypocalcemia ;Presence or absence of Hashimoto’s thyroiditis in postoperative pathology reports; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Sex;Body Mass Index (BMI);Type of thyroid cancer;Type of surgery;Number of central lymph nodes and number of metastatic lymph nodes documented in postoperative pathology reports; | — |
Countries
China
Contacts
Public ContactYusheng Ye
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed