Early-stage lung cancer
Conditions
Interventions
Gold Standard:pulmonary function test (PFT)
Index test:Ventilation Defect Percentage (VDP), Quantitative Perfusion Defect Percentage (QDP), and the Ventilation-Perfusion (V/Q) Match Ratio
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-80 years; 2.Patients with primary lung cancer scheduled for segmentectomy or lobectomy; 3.Preoperative expected survival >=1 year; 4.Lung function permits surgical intervention; 5.Able to undergo MRI examination and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Have obvious contraindications for MRI (such as pacemakers, metal implants); 2. Have severe heart failure, renal dysfunction or other systemic diseases that are unsuitable for MRI examination; 3. Pregnant or lactating women; 4. Those who cannot complete postoperative follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in functional lung MRI parameters;Correlation between functional lung MRI parameters and pulmonary function test indices; | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in the magnitude of change in functional lung MRI parameters between patients undergoing segmentectomy and lobectomy;Predictive value of preoperative functional lung MRI for postoperative pulmonary function;Agreement between functional lung MRI ventilation map and CT lung volume distribution; | — |
Countries
China
Contacts
Public ContactShi Jingyun
Shanghai Pulmonary Hospital
Outcome results
None listed