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The changes of xerostomia and caries risk induced by radiotherapy under the protection of the personalized PMMA oral stents in nasopharyngeal carcinoma patients

Research on Oral Health Management of Nasopharyngeal Cancer Radiotherapy Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600122026
Enrollment
Unknown
Registered
2026-04-08
Start date
2019-06-12
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasopharyngeal Cancer

Interventions

Experimental group:each patient was given a personalized PMMA oral stent, and instructed to wear it during position, set-up and the irradiation.

Sponsors

West China Hospital of Stomatology, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria were as follows: Patients aged 18-70 years;NPC patients confirmed by histopathology and received radiotherapy and chemotherapy for the first time; Patients who complied with this study and voluntarily signed an informed consent form.

Exclusion criteria

Exclusion criteria: The exclusion criteria were as follows: Patients with severe systemic disease, such as diabetes, severe cardiovascular and cerebrovascular complications. Patients with severe cognitive, mental, and language disorders.

Design outcomes

Primary

MeasureTime frame
The flow rate of saliva;Cariostat Caries Susceptibility;DMF index;—

Secondary

MeasureTime frame
Plaque Index;Saliva pH;Grading of oral radiation-induced mucositis (NCI-CTC);—

Countries

China

Contacts

Public ContactJiang Li

West China Hospital of Stomatology, Sichuan University

28996073@qq.com+86 135 4808 9334

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026