Sepsis
Conditions
Interventions
Blood perfusion group A:N/A
Blood perfusion group B:N/A
Sponsors
Harbin Medical University Affiliated First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Meets the diagnostic criteria of Sepsis3.0; 3. Admit to the intensive care unit; 4. Receive at least 24 hours of imipenem treatment; 5. Accept HA380 blood perfusion therapy; 6. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Individuals with HIV infection or other immunodeficiency diseases; 3. Patients with combined active bleeding, disseminated intravascular coagulation, thrombosis, or thrombotic diseases; 4. Patients with a history of combined organ transplantation; Patients with unstable infarction caused by combined cardiovascular accidents; New York Heart Association (NYHA) Grade IV decompensated heart failure subjects; Subjects with chronic kidney disease (CKD) stage 5 or above; Subjects with end-stage liver failure. 5. Received blood perfusion therapy within one week before enrollment; 6. Individuals who are allergic to any component of the upcoming blood perfusion device; 7. Patients who cannot comply with research arrangements and refuse to sign informed consent forms; 8. Other situations deemed unsuitable for inclusion by researchers;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Drug concentration; | — |
Countries
China
Contacts
Public ContactKai Kang
The First Affiliated Hospital of Harbin Medical University
Outcome results
None listed