Postherpetic neuralgia
Conditions
Interventions
Intervention group:Thoracic spinal nerve root block combined with pulsed radiofrequency modulation
Control group:Pulsed radiofrequency modulation alone
Sponsors
The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria for PHN: herpes zoster course >=1 month and VAS score >=40 points at the time of visit; 2) Age >=18 years and <=85 years; 3) Herpetic skin lesions located in the thoracic spinal nerve innervation area (T1-T12); involving <=4 segments; 4) No prior treatment with PRF, nerve block, or other minimally invasive interventional therapies before enrollment; 5) Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with severe cardiopulmonary insufficiency, severe hepatic or renal insufficiency, or hematological disorders; 2) Patients with skin lesions or local infection at the puncture site; 3) Patients with poorly controlled diabetes (fasting blood glucose >=10.0 mmol/L); 4) Patients with abnormal coagulation function; 5) Patients with allergy to local anesthetics or other drugs used in this study, or those otherwise unsuitable for nerve block; 6) Pregnant or lactating women; 7) Patients with psychiatric disorders or cognitive dysfunction who cannot adequately understand the study assessment scales.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain VAS score at 1 month; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in pain at 1 day, 1 week, 1 month, and 3 months postoperatively;Inflammatory indicators;Insomnia Severity Index, ISI;Patient Health Questionnaire-9, PHQ-9;Generalized Anxiety Disorder-7, GAD-7;Postoperative complications and adverse reactions;Dosage of analgesic drugs and remedial drugs; | — |
Countries
China
Contacts
Public ContactWang Yingfeng
The 940th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army
Outcome results
None listed