Knee Meniscal Injury
Conditions
Interventions
Intervention group:Intra-articular injection of ozone (O?) combined with platelet-rich plasma (PRP) into the knee joint, administered once every 3 weeks for a total of three injections, with an interv
Control group:Intra-articular injection of platelet-rich plasma (PRP) into the knee joint, administered once every 3 weeks for a total of three injections, with a total intervention period of 9 weeks.
Sponsors
Mianyang 404 Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40–85 years, with no restriction on sex; 2. Presence of knee pain, with no recent history of trauma; 3. MRI findings indicating Stoller grade I–IV lesions, consistent with a diagnosis of meniscal injury.
Exclusion criteria
Exclusion criteria: 1. Presence of systemic infection; 2. Hematologic disorders; 3. Malignancy, including confirmed or suspected cases; 4. Patients with poorly controlled diabetes mellitus; 5. Presence of other joint-related diseases, such as rheumatoid arthritis or acute gouty arthritis; 6. Patients who refuse intra-articular injection therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stoller grading assessed by MRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Visual Analog Scale (VAS);Knee function (WOMAC score);Barthel Index (BI); | — |
Countries
China
Contacts
Public ContactJihong Zhang
Affiliation of the Registrant:Mianyang 404 Hospital
Outcome results
None listed