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To study the mechanism of fever related to epidural labor analgesia based on metabolomics

To study the mechanism of fever related to epidural labor analgesia based on metabolomics

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121993
Enrollment
Unknown
Registered
2026-04-08
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fever related to epidural labor analgesia

Interventions

Epidural analgesia group: postpartum women without fever after epidural analgesia:None
High fever group: Pregnant women who experience fever after epidural analgesia: highest body temperature during labor>38 ?:None
Control group: parturients who did not receive epidural analgesia during delivery:None
Low fever group: Pregnant women who experience fever after epidural analgesia, with the highest body temperature during labor between 37.5-38 ?:None

Sponsors

Tianjin Central Hospital of Gynecology Obstetrics
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Full-term pregnancy, single pregnancy, ASA grade II, no history of fever one week before delivery, the epidural analgesia group voluntarily chose epidural analgesia and signed the consent form.

Exclusion criteria

Exclusion criteria: Combined acute and severe hypertension, diabetes, other serious systemic diseases, fetal distress or abnormal fetal heart rate, and drug allergies related to this study.

Design outcomes

Primary

MeasureTime frame
Analysis and detection of plasma metabolites in parturients;The degree of stress response of the parturient;

Secondary

MeasureTime frame
The changes in body temperature of perinatal parturients and the fever situation after analgesia;Observe the effects of ERMF on fetuses and newborns;Observe the effect of ERMF on parturients;

Countries

China

Contacts

Public ContactXu Jiangang

Tianjin Central Hospital of Gynecology Obstetrics

tjyzxet@163.com+86 22 58287905

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026