Patients with heart valve disease (HVD) complicated with atrial fibrillation (AF) have cardiac function of Class III-IV
Conditions
Interventions
Experimental group:Cardiac valve replacement + Modified BRCA + Left atrial appendage closure
Control group:Cardiac valve replacement + left atrial appendage closure
Sponsors
Yuebei People’s Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for HVD and AF, and have been confirmed by echocardiography and other methods before surgery. 2. Have no surgical contraindications. 3. Have no history of cardiac surgery. 4. Have cardiac function of >= grade III. 5. Have complete medical records and have provided informed consent for this study.
Exclusion criteria
Exclusion criteria: 1. Concurrent infectious diseases. 2. Concurrent malignant tumors. 3. Pregnant and lactating patients. 4. Concurrent cardiac cachexia. 5. Concurrent liver and kidney dysfunction. 6. Congenital cardiac structural abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative sinus rhythm recovery rate;The occurrence of stroke; | — |
Secondary
| Measure | Time frame |
|---|---|
| Aortic cross-clamping time, radiofrequency ablation time, and extracorporeal circulation duration;Postoperative drainage volume, ICU stay duration, total hospitalization duration, and pacemaker implantation rate;Perform echocardiographic assessment and compare the patient's left atrial diameter, left atrial ejection fraction, and left ventricular shortening fraction; | — |
Countries
China
Contacts
Public ContactHe Weibo
Yuebei People’s Hospital
Outcome results
None listed