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Predicting the Risk of Early-Stage Digestive Malignancies Using an Integrated Machine Learning Model Incorporating GDF-15 and Multiple Biomarkers

Predicting the Risk of Early-Stage Digestive Malignancies Using an Integrated Machine Learning Model Incorporating GDF-15 and Multiple Biomarkers

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121976
Enrollment
Unknown
Registered
2026-04-07
Start date
2025-04-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive Malignancies

Interventions

Digestive Malignancies:none
Control group:None

Sponsors

Tianjin Medical University Cancer Institute and Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All patients with gastrointestinal tumors are newly diagnosed, and no treatment has been administered before blood collection; 2. Primary gastrointestinal malignancies confirmed by histopathology; 3. All study participants voluntarily participated and signed informed consent; 4. Clinical data is complete and follow-up can be conducted; 5. Serum samples of the healthy control group are all stored in the sample bank; 6. Serum samples of patients with gastrointestinal tumors and liver cirrhosis are all stored in the sample bank; 7. Only cases with complete blood samples can be included in this study.

Exclusion criteria

Exclusion criteria: 1. Missing clinical information; 2. Tumor patients who have received treatment before the initial diagnosis; 3. Patients who develop other malignant tumors during follow-up and die from other malignant tumors;

Design outcomes

Primary

MeasureTime frame
Sensitivity;specificity;

Secondary

MeasureTime frame
Carbohydrate Antigen 19-9 ;Carcinoembryonic Antigen;

Countries

China

Contacts

Public ContactRanliang Cui

Tianjin Medical University Cancer Institute and Hospital

cuiranliang@163.com+86 151 2246 7665

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026