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The effectiveness and safety of virtual reality assisted binocular vision therapy in the treatment of amblyopia after congenital cataract surgery: a two center randomized controlled study

The effectiveness and safety of virtual reality assisted binocular vision therapy in the treatment of amblyopia after congenital cataract surgery: a two center randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121967
Enrollment
Unknown
Registered
2026-04-07
Start date
2026-04-07
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital cataract

Interventions

control group:Covering therapy
VR therapy group:Virtual reality assisted binocular vision therapy for treatment

Sponsors

The Zhongshan Ophthalmic Center,Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1) Age 3-10 years old, diagnosed with amblyopia; 2) Visited the Refractive and Adolescent Myopia Prevention and Control Outpatient Clinic, with a previous diagnosis of bipolar disorder Congenital cataract in one or both eyes, and the cataract has already passed through the white eye Obstacle removal surgery and implantation of artificial lens, at least 3 months after surgery; 3) The best corrected visual acuity (BCVA) for both eyes after surgery was = 0.05; 4) Can cooperate to complete VR training and regular follow-up; 5) The subjects and their legal guardians sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1.Exclusion criteria: 1) Explicit strabismus or nystagmus; 2) There are significant postoperative complications such as posterior chamber obstruction, glaucoma, and intraocular inflammation; 3) Merge other eye diseases that affect visual function (such as macular degeneration, visual impairment, etc.) Neural developmental abnormalities, etc.); 4) Combining systemic diseases such as epilepsy, history of traumatic brain injury, fear of heights, dizziness, etc Not suitable for VR trainers; 5) Received other visual training methods within 4 weeks prior to training; 6) Failed to cooperate with the training and follow-up plan.

Design outcomes

Primary

MeasureTime frame
Best Corrected Visual Acuity (BCVA);

Secondary

MeasureTime frame
Proportion of BCVA improvement >=1 line;

Countries

China

Contacts

Public ContactXiao Yang

The Zhongshan Ophthalmic Center,Sun Yat-sen University

yangxiao@gzzoc.com+86 20 8733 0410

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026