Randomized Controlled Trial of Transcranial Random Noise Stimulation for Improving Symptoms in Children with Attention-Deficit/Hyperactivity Disorder

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600121966

Enrollment

Unknown

Registered

2026-04-07

Start date

2026-04-07

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

attention-deficit/hyperactivity disorder

Interventions

Control group:Sham transcranial random noise stimulation and cognitive training

Test group:Transcranial random noise stimulation and cognitive training

Eligibility

Sex/Gender

All

Age

6 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1.Aged 6 to 12 years (inclusive); any gender. 2.Diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) according to DSM-5 criteria, confirmed through semi-structured interviews with patients and parents, neurological examinations conducted by pediatricians or child development specialists; any subtype is eligible. 3.Right-handed, to ensure consistency in the placement of brain stimulation electrodes.

Exclusion criteria

Exclusion criteria: 1.A previous or current diagnosis of organic brain diseases such as epilepsy, traumatic brain injury, cerebrovascular disease, or brain tumor; 2.Intracranial hypertension, skull defect; severe cardiac disease, physical illness, or other conditions with unstable vital signs; acute phase of cerebrovascular disease; 3.A personal or first-degree family history of epilepsy or febrile seizures; 4.IQ < 70 (assessed by the Wechsler Intelligence Scale for Children, Fourth Edition) or presence of pervasive developmental disorders, autism spectrum disorder; 5.Comorbid primary psychiatric disorders such as major depressive disorder, bipolar disorder, schizophrenia, obsessive-compulsive disorder, or severe anxiety disorder; 6.Presence of implanted devices such as deep brain stimulators (DBS), metal implants in the head, pacemakers, cochlear implants, or other contraindications to electrical stimulation; 7.History of adverse reactions to electrical stimulation; 8.Severe visual or hearing impairments, or physical disabilities that prevent cooperation with cognitive training and assessment.

Design outcomes

Primary

Measure	Time frame
SNAP-IV Rating Scale and its subscales: Inattention (IA) and Hyperactivity/Impulsivity (HI);	—

Secondary

Measure	Time frame
Comprehensive Behavior Rating Scale: Conners;Wisconsin Card Sorting Test;Digit Cancellation Test (DCT);Functional Near-Infrared Spectroscopy;	—

Countries

China

Contacts

Public ContactMao Yurong

The Seventh Affiliated Hospital Sun Yat-sen University

maoyr@mail.sysu.edu.cn+86 755 81206511

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026