Undergo cochlear implant surgery
Conditions
Interventions
Total Intravenous Anesthesia (TIVA) group:The initial dose is 0.5 µ g/ml, and the modified Dixon sequential method is used, which adjusts the dose of the next patient based on the CM monitoring result
volatile inhalational (INHA) group:The initial dose is 0.5 MAC, and the modified Dixon sequential method is used, which adjusts the dose of the next patient based on the CM monitoring results (success
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-75 years old; 2.ASA classification = II; 3.Patients scheduled for cochlear implantation; 4.The definition of residual hearing value on the surgical side is: Air-Conduction Auditory Brainstem Response (AC-ABR) = 95 dB nHL or pure-tone audiometry (PTA) = 120 dBHL;
Exclusion criteria
Exclusion criteria: 1.Patients with vestibulocochlear nerve/cochlear anatomical abnormalities; 2.Patients who are allergic to propofol, sevoflurane, and opioids or have contraindications to their use; 3.Patients with combined severe central nervous system, respiratory, circulatory, and cognitive impairments;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| median effective dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative awareness;90% effective dose;Postoperative satisfaction;Hemodynamic indicators; | — |
Countries
China
Contacts
Public ContactJingjie Li
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed