breast carcinoma
Conditions
Interventions
Gold Standard:Intraoperative SLNB localization and frozen section analysis of SLNB
Index test:1.A risk prediction model for SLNM based on clinical-pathological and multimodal ultrasound data
2.A radiomics score based on breast ultrasound and ALN multimodal ultrasound imaging data
3.A combined diagnostic model integrating the clinical and radiomics models
Sponsors
Cancer Hospital Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Female patients with cT1-2N0M0 breast cancer; 2.Age = 18 years; 3.Patients scheduled to undergo intraoperative sentinel lymph node biopsy (SLNB); 4.Patients who voluntarily participate in the study and have provided written informed consent;
Exclusion criteria
Exclusion criteria: 1.History of prior ipsilateral breast or axillary surgery, radiotherapy, or receipt of neoadjuvant chemotherapy; 2.Patients with bilateral breast cancer; 3.Patients unable to undergo the complete ultrasound examination or needle biopsy; 4.Pregnant patients or those with a known allergy to ultrasound contrast agents; 5.Patients with incomplete clinical-pathological data or ultrasound image;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic concordance rate of CEUS-guided biopsy of sentinel lymph nodes;Accuracy of percutaneous contrast-enhanced ultrasound (CEUS) lymphography in localizing sentinel lymph nodes (SLNs);Diagnostic performance of intravenous contrast-enhanced ultrasound (CEUS) for characterizing sentinel lymph node metastasis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Contrast-enhanced ultrasound enhancement patterns of sentinel lymph nodes; | — |
Countries
China
Contacts
Public ContactFeng Li
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed