Patients undergoing gastrointestinal endoscopy
Conditions
Interventions
QQ:Endoscope insertion 30 s–2 min after drug administration
HQ:Endoscope insertion 2-4 min after completion of drug administration
Sponsors
Guangdong Provincial People's Hospital, Zhuhai Hospital (Jinwan Central Hospital of Zhuhai)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing painless gastrointestinal endoscopy 2. ASA physical status class I–III 3. New York Heart Association (NYHA) functional class I–II 4. Aged 18 to 70 years
Exclusion criteria
Exclusion criteria: 1. Patients with hypersensitivity to propofol 2. Patients with disturbance of consciousness, poor expression ability, or inability to cooperate 3. Uncontrolled life-threatening circulatory or respiratory diseases, including: Acute coronary syndrome, Severe hypertension (SBP >= 180 mmHg or DBP >= 110 mmHg), Severe arrhythmia, Heart failure, Pericardial effusion, Acute respiratory tract infection, Pulmonary edema, Pleural effusion, Asthma in acute attack, Active massive hemoptysis 4. SpO2 32 kg/m^2) 6. Acute upper gastrointestinal bleeding 7. Gastrointestinal obstruction with gastric content retention 8. Severe anemia (Hb < 60 g/L) 9. Hepatic dysfunction (Child-Pugh class C or worse) 10. Patients in whom the procedure was terminated due to unexpected events during examination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of choking and cough;VAS fatigue score;recovery time;discharge time; | — |
Countries
China
Contacts
Public ContactHongqian Huang
Guangdong Provincial People's Hospital, Zhuhai Hospital (Jinwan Central Hospital of Zhuhai).
Outcome results
None listed