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To evaluate the efficacy and safety of bovine pericardial biologic patch for VATS pulmonary resection in elderly patients

To evaluate the efficacy and safety of bovine pericardial biologic patch for VATS pulmonary resection in elderly patients

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121919
Enrollment
Unknown
Registered
2026-04-07
Start date
2025-03-25
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer with surgical indications

Interventions

Group A:When the lung tissue was cut during the operation, disposable endoscopic anastomat and bovine pericardial patch were used
Group B:Intraoperative resection of lung tissue was performed with disposable endoscopic anastomat

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Male or female, >=60 years old; 2. The function of the heart, lungs, liver, kidney and other important organs is normal or basically normal; 3. Undergo a single-hole VATS pneumonectomy (including wedge resection, segmentectomy, or lobectomy).

Exclusion criteria

Exclusion criteria: 1. It is not suitable for surgical treatment, such as preoperative fever, acute infection, myocardial infarction, acute cerebral infarction, deep vein thrombosis Abnormal indicators of formation and coagulation function, preoperative tumor staging not suitable for surgical treatment, multiple tumors lesion; 2. The lung conditions are complex, which may affect the judgment of intraoperative and postoperative indicators, such as severe chronic obstruction Sexual lung disease, recurrent pneumothorax, history of previous pulmonary surgery, history of tuberculosis, history of empyema / A history of pleurisy, etc., may result in severe pleural adhesions, anatomic variations such as pulmonary sequestration/bronchial malformation, etc Pulmonary fibrosis; 3. Poor preoperative cardiopulmonary function assessment, poor general nutrition and mental state can not tolerate surgery; 4. Patients with basic diseases requiring long-term oral anticoagulants before surgery; 5. Patients or family members refused surgical treatment, or did not have surgery for other reasons;

Design outcomes

Primary

MeasureTime frame
Air leakage rate and blood infiltration rate of pulmonary incisal margin during operation;

Secondary

MeasureTime frame
The incidence of persistent air leakage (PAL) of the lung;Postoperative air leakage rate;Adverse event incidence rate;

Countries

China

Contacts

Public ContactBentong Yu

The First Affiliated Hospital of Nanchang University

yubentong@126.com+86 791 88692201

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026