Non-small cell lung cancer with surgical indications
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female, >=60 years old; 2. The function of the heart, lungs, liver, kidney and other important organs is normal or basically normal; 3. Undergo a single-hole VATS pneumonectomy (including wedge resection, segmentectomy, or lobectomy).
Exclusion criteria
Exclusion criteria: 1. It is not suitable for surgical treatment, such as preoperative fever, acute infection, myocardial infarction, acute cerebral infarction, deep vein thrombosis Abnormal indicators of formation and coagulation function, preoperative tumor staging not suitable for surgical treatment, multiple tumors lesion; 2. The lung conditions are complex, which may affect the judgment of intraoperative and postoperative indicators, such as severe chronic obstruction Sexual lung disease, recurrent pneumothorax, history of previous pulmonary surgery, history of tuberculosis, history of empyema / A history of pleurisy, etc., may result in severe pleural adhesions, anatomic variations such as pulmonary sequestration/bronchial malformation, etc Pulmonary fibrosis; 3. Poor preoperative cardiopulmonary function assessment, poor general nutrition and mental state can not tolerate surgery; 4. Patients with basic diseases requiring long-term oral anticoagulants before surgery; 5. Patients or family members refused surgical treatment, or did not have surgery for other reasons;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Air leakage rate and blood infiltration rate of pulmonary incisal margin during operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of persistent air leakage (PAL) of the lung;Postoperative air leakage rate;Adverse event incidence rate; | — |
Countries
China
Contacts
The First Affiliated Hospital of Nanchang University