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Study on the Correlation of ET-1 and sICAM-1 with Left Ventricular Hypertrophy in Patients with Primary Hypertension

Study on the Correlation of ET-1 and sICAM-1 with Left Ventricular Hypertrophy in Patients with Primary Hypertension

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121918
Enrollment
Unknown
Registered
2026-04-07
Start date
2026-04-25
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Essential Hypertension

Interventions

LVH group vs. Non-LVH group:None

Sponsors

People's Hospital of Jianyang City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. All patients meet the diagnostic criteria for hypertension as outlined in the 2018 Revision of the Chinese Guidelines for the Prevention and Treatment of Hypertension and are diagnosed with essential hypertension; 2. Aged 18 to 85 years; 3. Have complete clinical data.

Exclusion criteria

Exclusion criteria: 1.Patients with secondary hypertension; 2. Patients complicated with severe arrhythmias (e.g., atrial fibrillation/flutter, ventricular fibrillation/flutter), heart failure (NYHA class III–IV), severe valvular heart disease, or cardiomyopathy; 3. Patients who have experienced an acute coronary syndrome within the past 3 months; 4. Patients complicated with diabetes mellitus (type 1 or type 2); 5. Patients with autoimmune diseases, malignant tumors, or active infections; 6. Patients with severe hepatic or renal dysfunction ; 7. Patients who have taken medications within 1 month prior to enrollment that may significantly affect ET-1 or sICAM-1 levels and are not part of routine antihypertensive therapy (e.g., systemic glucocorticoids, immunosuppressants); 8. Pregnant or breastfeeding women.

Design outcomes

Primary

MeasureTime frame
Primary predictor;Primary predictor;Primary outcome measure;(sICAM-1) Primary predictor;

Countries

China

Contacts

Public ContactXiangbin Xiao

People's Hospital of Jianyang City

664061688@qq.com+86 28 27238006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026