Vertebral compression fracture
Conditions
Interventions
Control Group:None
Sponsors
Beijing Friendship Hospital ,Capital Medical University
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Postmenopausal women or men older than 50 years; 2. Thoracolumbar vertebral compression fractures with mild or no trauma; 3. First surgery; 4. VAS score >= 6; 5. The same surgical team;
Exclusion criteria
Exclusion criteria: 1. Secondary osteoporosis, bone metastasis after bone tumor; 2. Vertebral tuberculosis, bacterial infection; 3. Severe coagulation and bleeding dysfunction that cannot be corrected; 4. Previous allergy history to bupivacaine liposomes. 5. Those who have not obtained informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score at 24 hours after PVP surgery in patients treated with bupivacaine liposome injection; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score at rest and during activity;Heart rate (HR);Mean arterial pressure (MAP);Respiratory rate (RR);Pulse oximetry saturation (SpO2);Opioid consumption during perioperative period;Length of hospital stay;Fall risk assessment score;Activities of daily living (ADL) score;Sleep duration; | — |
Countries
China
Contacts
Public ContactFei Qi
Beijing Friendship Hospital ,Capital Medical University
Outcome results
None listed