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The impact of chemotherapy and endocrine therapy on sexual function in young female breast cancer patients: A single-center prospective cross-sectional study

The impact of chemotherapy and endocrine therapy on sexual function in young female breast cancer patients: A single-center prospective cross-sectional study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121888
Enrollment
Unknown
Registered
2026-04-07
Start date
2026-04-15
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Interventions

Hr-patient group:None
HR+ patient group:None
Healthy group:None

Sponsors

Sun Yat-sen University Cancer Canter
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion: 1. Healthy control group: 18-50-year-old women without breast cancer, who have not undergone chemotherapy or endocrine therapy, have a stable partner and engage in sexual activity; 2. HR+ patient group: 18-50-year-old female patients with stage I-III breast cancer, after chemotherapy, 2-5 years of OFS + endocrine therapy, have a stable partner and engage in sexual activity; 3. HR- patient group: 18-50-year-old premenopausal female patients with stage I-III breast cancer, 2-5 years after chemotherapy, have not used OFS, and have a stable partner and engage in sexual activity.

Exclusion criteria

Exclusion criteria: Suffering from genital-related diseases; suffering from mental disorders; suffering from other serious systemic diseases and tumors; having poor compliance.

Design outcomes

Primary

MeasureTime frame
FSFI score;

Secondary

MeasureTime frame
Short STAI score;Menstrual situation;

Countries

China

Contacts

Public ContactJun Tang

Sun Yat-sen University Cancer Canter

tangjun@sysucc.org.cn+86 137 2488 7991

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026