Lumbar degenerative disease
Conditions
Interventions
Liposomal bupivacaine group:Local infiltration anesthesia was performed around the psoas major muscle and the surgical incision using 20 mL of liposomal bupivacaine (266 mg).
Ropivacaine group:Local infiltration anesthesia with 20 mL of 0.5% ropivacaine around the psoas major muscle and the surgical incision.
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age 18–75 years, either sex, with an ASA physical status classification of I–III. 2.Diagnosed with lumbar disc herniation or lumbar spinal stenosis, with failure of at least 3 months of conservative treatment, and scheduled to undergo single-level OLIF. 3.No history of allergy to local anesthetics and no severe cardiopulmonary, hepatic, or renal insufficiency.
Exclusion criteria
Exclusion criteria: 1.Long-term preoperative use of opioids or patient-controlled analgesia pumps. 2.Presence of psychiatric disorders or cognitive impairment that would preclude cooperation with pain assessment. 3.Presence of severe chronic comorbidities, such as cardiac disease or renal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS scores for back and leg pain in 72 h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative opioid use;Improvement in lumbar function;Quality of life improvement;Pain satisfaction score; | — |
Countries
China
Contacts
Public ContactZeng Jiancheng
West China Hospital, Sichuan University
Outcome results
None listed