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Association Analysis of Perioperative Systolic Blood Pressure Variability with Postoperative Prognosis in Patients Undergoing Transcatheter Intracranial Thrombectomy

Study on the Ideal Blood Pressure Level During Perioperative Period of Intracranial Vascular Thrombectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121822
Enrollment
Unknown
Registered
2026-04-03
Start date
2026-04-04
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute stroke

Interventions

Low perioperative blood pressure variability group:none
Medium perioperative blood pressure variability group:none
High perioperative blood pressure variability group:none

Sponsors

The First People's Hospital of Lianyungang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for acute ischemic stroke; 2. Anterior circulation large vessel occlusion confirmed by cerebral angiography; 3. Time from onset to endovascular treatment <= 24 h; 4. Age 18–85 years; 5. Modified Rankin Scale (mRS) score <= 1 before onset, excluding patients with significant pre-existing functional impairment; 6. Underwent transcatheter intracranial thrombectomy (including stent retriever thrombectomy, aspiration thrombectomy, combined thrombectomy, or balloon-assisted thrombectomy), excluding patients with stent implantation.

Exclusion criteria

Exclusion criteria: 1. Baseline National Institutes of Health Stroke Scale (NIHSS) score > 28; 2. History of hemorrhagic disorders, or intracranial hemorrhage and evidence of active bleeding shown on head CT; 3. Severe cardiac, hepatic, renal, or pulmonary insufficiency; 4. Extensive core infarct volume with no surgical benefit judged by the treatment team; 5. Postoperative modified Thrombolysis in Cerebral Infarction (mTICI) grade not reaching 2b or higher; 6. Patients with missing perioperative blood pressure monitoring data or loss to follow-up at 90 days postoperatively.

Design outcomes

Primary

MeasureTime frame
Modified Rankin Scale (mRS) score at 90 days postoperatively;symptomatic intracranial hemorrhage;

Countries

China

Contacts

Public ContactYang Qianqian

The First People's Hospital of Lianyungang

1161880131@qq.com+86 189 6132 2716

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026