Acute stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for acute ischemic stroke; 2. Anterior circulation large vessel occlusion confirmed by cerebral angiography; 3. Time from onset to endovascular treatment <= 24 h; 4. Age 18–85 years; 5. Modified Rankin Scale (mRS) score <= 1 before onset, excluding patients with significant pre-existing functional impairment; 6. Underwent transcatheter intracranial thrombectomy (including stent retriever thrombectomy, aspiration thrombectomy, combined thrombectomy, or balloon-assisted thrombectomy), excluding patients with stent implantation.
Exclusion criteria
Exclusion criteria: 1. Baseline National Institutes of Health Stroke Scale (NIHSS) score > 28; 2. History of hemorrhagic disorders, or intracranial hemorrhage and evidence of active bleeding shown on head CT; 3. Severe cardiac, hepatic, renal, or pulmonary insufficiency; 4. Extensive core infarct volume with no surgical benefit judged by the treatment team; 5. Postoperative modified Thrombolysis in Cerebral Infarction (mTICI) grade not reaching 2b or higher; 6. Patients with missing perioperative blood pressure monitoring data or loss to follow-up at 90 days postoperatively.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale (mRS) score at 90 days postoperatively;symptomatic intracranial hemorrhage; | — |
Countries
China
Contacts
The First People's Hospital of Lianyungang