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Effects of pain neuroscience education on pain,cognition and motor function in patients with knee osteoarthritis

Effects of pain neuroscience education on pain,cognition and motor function in patients with knee osteoarthritis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121815
Enrollment
Unknown
Registered
2026-04-03
Start date
2025-07-21
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early-stage knee osteoarthritis

Interventions

Groups BME:None
Groups PNE:None

Sponsors

Xuzhou Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Meets the diagnostic criteria of the Early Knee Osteoarthritis Diagnosis and Non-Surgical Treatment Guidelines (2024 Edition), with chronic pain as the primary clinical symptom. 2.Lower limb muscle strength grade 4 or higher, unilateral onset; 3.This study recruited participants aged 40 to 65 years, with no gender restrictions. 4.The patient is in good physical condition with high compliance, and can complete exercise training independently or with assistance. 5.Voluntary participation in this study and signing of the informed consent form;

Exclusion criteria

Exclusion criteria: 1.Lower limb bone or joint lesions caused by other diseases such as rheumatic immunological disorders and renal osteodystrophy; 2.Patients with a history of joint trauma (e.g., knee fracture, meniscus or ligament injury); 3.patients with indications for knee arthroplasty; 4.patients with severe obesity (BMI> 37.5 kg/m²); 5.Patients with severe cardiac, cerebral, hepatic, renal, or hematopoietic disorders, as well as malignancies or psychiatric conditions; 6.Concurrently initiating this study with new drugs or novel therapies for KOA, or concurrently participating in other trials; 7.Poor adherence, unable to participate in the implementation of the intervention program throughout;

Design outcomes

Primary

MeasureTime frame
gait analysis;pain self-efficacy questionnaire,PSEQ;tampa scale for kinesiophobia ,TSK;pain catastrophizing scale,PCS;

Secondary

MeasureTime frame
isokinetic muscle strength test;the western ontario mcmaster universities,WOMAC;

Countries

China

Contacts

Public ContactDing Wencheng

Xuzhou Rehabilitation Hospital

1505811105@qq.com+86 516 8510 0877

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026