Early-stage knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria of the Early Knee Osteoarthritis Diagnosis and Non-Surgical Treatment Guidelines (2024 Edition), with chronic pain as the primary clinical symptom. 2.Lower limb muscle strength grade 4 or higher, unilateral onset; 3.This study recruited participants aged 40 to 65 years, with no gender restrictions. 4.The patient is in good physical condition with high compliance, and can complete exercise training independently or with assistance. 5.Voluntary participation in this study and signing of the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Lower limb bone or joint lesions caused by other diseases such as rheumatic immunological disorders and renal osteodystrophy; 2.Patients with a history of joint trauma (e.g., knee fracture, meniscus or ligament injury); 3.patients with indications for knee arthroplasty; 4.patients with severe obesity (BMI> 37.5 kg/m²); 5.Patients with severe cardiac, cerebral, hepatic, renal, or hematopoietic disorders, as well as malignancies or psychiatric conditions; 6.Concurrently initiating this study with new drugs or novel therapies for KOA, or concurrently participating in other trials; 7.Poor adherence, unable to participate in the implementation of the intervention program throughout;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gait analysis;pain self-efficacy questionnaire,PSEQ;tampa scale for kinesiophobia ,TSK;pain catastrophizing scale,PCS; | — |
Secondary
| Measure | Time frame |
|---|---|
| isokinetic muscle strength test;the western ontario mcmaster universities,WOMAC; | — |
Countries
China
Contacts
Xuzhou Rehabilitation Hospital