Overweight/Mildly Obese
Conditions
Interventions
Overweight Intervention Group:This experiment was a self before and after control.Dietary guidance was given, daily dietary energy intake was 800~1500Kcal, to ensure the daily water intake of 2000ml,
Mild obesity intervention group:This experiment was a self before and after control.Dietary guidance was given, daily dietary energy intake was 800~1500Kcal, to ensure the daily water intake of 2000ml
Sponsors
Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. According to the diagnostic criteria of the Guidelines for the Diagnosis and Treatment of Obesity (2024), body mass index (BMI) = body weight (kg)/height^2 (m^2), 24 kg/m^2 25% in men and > 30% in women. 2. Age 18-60 years old (including the threshold), male or female; 3. Did not participate in clinical research, or after participating in clinical research has stopped the drug elution for more than 6 months; 4. Be able to understand the procedures and methods of the study, be willing and able to maintain a stable diet and exercise lifestyle during the study period, and voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Use of psychoactive substances, drug abuse and dependence; 2. People who have had allergies to the components of the intervention used in this study; 3. Women who are pregnant or breastfeeding, or those who need to prepare for pregnancy; 4. Secondary obesity; 5. Patients with diabetes (except pre-diabetes), heart disease, liver and kidney insufficiency, mental disease, systemic infectious disease, gastrointestinal disease; 6. There is a deformity or deformity of the limb that affects the measurement of height and weight; 7. Those with a history of alcohol abuse within 6 months prior to screening; 8. Those who have taken any weight loss measures or medication in the 6 months prior to screening; 9. Factors judged by other researchers to be unsuitable for participation in the experiment exist.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight;Height;Waist circumference;Hip circumference;Skinfold thickness;Total body fat;Body fat rate;Total cholesterol, TC;Triglycerides, TG;Low-density lipoprotein cholesterol, LDL-C;High-density lipoprotein cholesterol, HDL-C;Body mass index, BMI;superconducting gravity gradiometer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure, BP;Aspartate aminotransferase, AST ;Alanine aminotransferase, ALT;Blood urea nitrogen, BUN;Creatinine, CR;Uric acid, UA;Serum interleukin-6;Adiponectin;Leptin;Blood glucose, BG;C-reactive protein,CRP;Satiety index; | — |
Countries
China
Contacts
Public ContactHui Liang
College of Public Health, Medical College, Qingdao University
Outcome results
None listed