Postoperative Sleep Disorder (PSD)
Conditions
Interventions
Sponsors
Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old; 2. Patients planning to undergo surgery (such as urology, hepatobiliary or other surgeries); 3. ASA I-III level; 4.BMI 18-28kg/m^2; 5.Informed consent, voluntary participation in the experiment, and signing of the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Patients with severe liver and kidney dysfunction, including hyperthyroidism, hypothyroidism, and pheochromocytoma, which affect drug metabolism; 2.Patients with mental or neurological disorders, long-term use of psychiatric drugs, or taking any sedatives, opioids, or sleep aids; 3.The subject has severe communication barriers due to severe hearing loss and other reasons; 4.Pregnant or lactating women; 5. Have a history of drug abuse, drug use, and alcoholism within the past two years. Alcoholism means drinking more than two units of alcohol on average every day (one unit of alcohol=360ml beer/45ml Baijiu/150ml wine with alcohol measurement>40%); 6. Patients admitted to the intensive care unit (ICU) after surgery; 7. Patients with long-term sleep disorders themselves; 8.Patients who refuse postoperative analgesic treatment; 9. Excluding patients whose anesthesia time spans between "daytime" and "nighttime";
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Postoperative Sleep Disorders; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum CRP, S100 ß, IL-6, and amyloid protein concentration levels;Pain Scroe;Changes in plasma inflammatory factor concentration levels;Sleep quality on the first day after surgery; | — |
Countries
China
Contacts
Public ContactLi Le
Zhujiang Hospital of Southern Medical University
Outcome results
None listed