Mechanical Ventilation
Conditions
Interventions
Case group:None
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-70 years; 2.Mechanical ventilation with endotracheal intubation; 3.Presence of a subclavian or internal jugular venous catheter;
Exclusion criteria
Exclusion criteria: 1.Age: 70 years; 2.Obesity (BMI >=30 kg/m²); 3.Pregnant or lactating women; 4.Pulmonary Diseases: Bronchial Asthma, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Fibrosis, Pleural Effusion, Pneumothorax, Pulmonary Embolism, Pulmonary Edema, Atelectasis, Acute Respiratory Distress Syndrome (ARDS); 5.Cardiac Diseases: arrhythmias, valvular regurgitation, cardiac dysfunction; 6.Shock: Lactate >1.8 mmol/L, blood pressure 0.05 µg/kg/min) for blood pressure maintenance; 7.Hypernatremia; 8.ECMO treatment; 9.Failure to provide informed consent;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of pulmonary perfusion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Driving Pressure;Blood pressure;Ppeak;Central venous pressure;PaO?/FiO? ratio;Heart rate;Pmean;PEEPi;PEEPtot;Ventilation-perfusion mismatch percentage;Intrapulmonary dead space percentage;Ventilation-perfusion matching percentage;Pulmonary shunt percentage;Pplat; | — |
Countries
China
Contacts
Public ContactYou Shang
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed