Atrial fibrillation
Conditions
Interventions
PFA group:Pulsed Field Ablation (PFA)
RFCA group: Radiofrequency catheter ablation (RFCA)
Sponsors
The Fourth Affiliated Hospital of Soochow University(Suzhou Dushu Lake Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.No gender restriction; 2.Aged 18 to 85 years (inclusive); 3.Patients with symptomatic atrial fibrillation who have a primary indication for catheter ablation; 4.Voluntarily participate in this trial and have signed the informed consent form; 5.Willing to comply with the relevant requirements of this trial and cooperate with the corresponding follow-up visits.
Exclusion criteria
Exclusion criteria: 1. Left atrial thrombus; 2. NYHA Class III–IV heart failure; 3. Patients with a history of unsuccessful radiofrequency ablation or recurrence; 4. Pregnant women; 5. Patients with a marked tendency to bleed or hematological disorders; 6. Acute or severe systemic infection, or significant abnormalities in liver or kidney function (laboratory values more than twice the upper limit of normal); 7. Patients with malignant tumors or end-stage diseases; 8. Acute coronary syndrome within the past 3 months; 9. Stroke or other cerebrovascular diseases within the past 3 months; 10. Patients deemed unsuitable for participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative 24-Hour Blood IL-6 Concentration;Postoperative 48-Hour Blood IL-6 Concentration;Hospital Anxiety and Depression Scale (HADS); | — |
Countries
China
Contacts
Public ContactLinlin Wang
The Fourth Affiliated Hospital of Soochow University(Suzhou Dushu Lake Hospital)
Outcome results
None listed