Post-thoracoscopic surgery pain
Conditions
Interventions
Experimental intervention group:Multimodal analgesia with intercostal nerve block combined with perioperative oral analgesics
Control intervention group:Postoperative patient-controlled intravenous opioid analgesia
Sponsors
Gansu Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years, regardless of gender; 2. Meet the indications for pulmonary surgery and scheduled to undergo thoracoscopic lobectomy/segmentectomy/partial pulmonary resection; 3. Scheduled to receive video-assisted thoracoscopic surgery (VATS); 4. Complete clinical data and meet the indications for anesthesia and surgery; 5. No mental illness or cognitive dysfunction, able to cooperate with all pain and recovery assessments; 6. American Society of Anesthesiologists (ASA) physical status classification ? or ?; 7. Voluntarily participate in this study and sign the written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Hypersensitivity to any component of the study drugs (bupivacaine colloid, celecoxib, paracetamol, tramadol); 3. Complicated with hemorrhagic diseases or severe coagulation dysfunction; 4. Preoperative history of chronic pain or intercostal neuralgia; 5. History of opioid abuse, alcohol or drug dependence; 6. Conversion to open thoracotomy during surgery for any reason; 7. Placement of >= 2 thoracic closed drainage tubes after surgery; 8. Patients judged by the investigators to have other clinical conditions unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative opioid consumption (converted to morphine equivalent);Visual Analogue Scale (VAS) pain score;Quality of Recovery-15 (QOR-15) score;Richards-Campbell Sleep Questionnaire (RCSQ) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Prince-Henry pain score;Times of rescue analgesia as per medical advice;Time to first ambulation after surgery;Incidence of postoperative adverse events and complications; | — |
Countries
China
Contacts
Public ContactYunjiu Gou
Gansu Provincial Hospital
Outcome results
None listed