Skip to content

Effects of Different Loading Conditions on Gait Asymmetry in Stroke Patients with Hemiplegia: A Randomized Crossover Study

Effects of Different Loading Conditions on Gait Asymmetry in Stroke Patients with Hemiplegia: A Randomized Crossover Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121728
Enrollment
Unknown
Registered
2026-04-02
Start date
2026-04-15
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Intervention Group 1:Non-weight-bearing Test – Washout Period – Affected Side Weight-bearing Test – Washout Period – Unaffected Side Weight-bearing Test – Washout Period – Trunk Weight-bearing Test –
Intervention Group 2:Non-weight-bearing Test – Washout Period – Affected Ankle and Contralateral Lumbar Weight-bearing Test – Washout Period – Trunk Weight-bearing Test – Washout Period – Unaffected A
Intervention Group 3:Affected Ankle and Contralateral Lumbar Weight-bearing Test – Washout Period – Non-weight-bearing Test – Washout Period – Affected Ankle Weight-bearing Test – Washout Period – Una
Intervention Group 4:Unaffected Ankle Weight-bearing Test – Washout Period – Affected Ankle Weight-bearing Test – Washout Period – Non-weight-bearing Test – Washout Period – Affected Ankle and Contral
Intervention Group 5:Unaffected Ankle Weight-bearing Test – Washout Period – Trunk Weight-bearing Test – Washout Period – Affected Ankle and Contralateral Lumbar Weight-bearing Test – Washout Period –

Sponsors

Shaanxi Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for stroke established by the National Cerebrovascular Disease Conference, with confirmation by CT or MRI. 2. First stroke onset, with a disease duration between 3 months and 2 years. 3. Unilateral hemiplegia. 4. Holden Functional Ambulation Classification >= level 2, able to walk independently without assistance for at least 10 meters. 5. Mini-Mental State Examination score >= 24 points, capable of understanding and following instructions. 6. Voluntarily participates and provides written informed consent.

Exclusion criteria

Exclusion criteria: 1. Presence of other neurological or musculoskeletal disorders that significantly affect walking function. 2. Severe dysfunction of vital organs (e.g., heart, lung, liver, or kidney). 3. Severe spasticity on the affected lower limb (Modified Ashworth Scale score > 2) or limited joint range of motion. 4. Severe visual or vestibular impairment affecting balance. 5. Participation in other clinical trials that may influence walking function.

Design outcomes

Primary

MeasureTime frame
Peak Moment Asymmetry Ratio of the Hip Joint (Unaffected vs. Affected Side) During Stance Phase;Peak Moment Asymmetry Ratio of the Knee Joint (Unaffected vs. Affected Side) During Stance Phase;Peak Moment Asymmetry Ratio of the Ankle Joint (Unaffected vs. Affected Side) During Stance Phase;

Secondary

MeasureTime frame
Step Length Asymmetry Ratio;Single-Limb Support Time Asymmetry Ratio;Sagittal Plane Range of Motion Asymmetry Ratio of the Hip Joint;Sagittal Plane Range of Motion Asymmetry Ratio of the Knee Joint;Sagittal Plane Range of Motion Asymmetry Ratio of the Ankle Joint;Overall Walking Speed and Cadence;

Countries

China

Contacts

Public ContactChen Longwei

Shaanxi Rehabilitation Hospital

3124331009@stu.xjtu.edu.cn+86 180 6676 3885

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026