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Research on Gut Microbiota and Its Metabolites in Patients with Neuropathic Pain after Spinal Cord Injury

Research on Gut Microbiota and Its Metabolites in Patients with Neuropathic Pain after Spinal Cord Injury

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121717
Enrollment
Unknown
Registered
2026-04-02
Start date
2025-02-14
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathic pain after spinal cord injury

Interventions

Neuralgia group:None
Non-neuralgia group:None
Control group :None

Sponsors

The Second Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patient group: Spinal cord injury within 6 months; The classification of the injured segments and the degree of injury was determined through neurological examination. Aged 18 to 70; Vital signs are stable; No severe diarrhea, inflammatory bowel disease or other gastrointestinal diseases, and no fecal microbiota transplantation treatment has been performed within half a year. No lung infection, bladder infection or respiratory tract infection; Patients without serious complications such as respiratory failure and heart failure; 2. Control group: Age 18-70 years; in good health; no severe diarrhea, inflammatory bowel disease or other gastrointestinal diseases, and no fecal microbiota transplantation treatment within the past half year.

Exclusion criteria

Exclusion criteria: 1. Patient group: Pain caused by spinal cord injury (such as musculoskeletal pain and visceral pain); pain from other disease sources; known malignant tumors; cognitive dysfunction or mental disorders. 2. Control group: Suffering from spinal cord injury; Have taken probiotics or antibiotics recently, experiencing pain in the body; gastrointestinal diseases; cognitive dysfunction or mental disorders.

Design outcomes

Primary

MeasureTime frame
Douleur Neuropathique 4 Questions;Self-rating anxiety scale;Self-rating Depression Scale;Pittsburgh Sleep Quality Index;Numerical rating scale;Basic demographic and clinical data (age, gender, height, weight, SCI degree, type, segment, time, etc.);

Countries

China

Contacts

Public ContactLi Yongmei

The Second Affiliated Hospital of Kunming Medical University

cherry20009666@139.com+86 137 0841 4280

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026