Locally Advanced Breast Cancer
Conditions
Interventions
Gold Standard:Postoperative pathology: pathological complete response (pCR) defined as no residual invasive carcinoma in breast and axillary lymph nodes (ypT0/is ypN0), per Chinese Expert Consensus on
Index test:1. Equipment: Supersonic Imaging Aixplorer ultrasound system (Supersonic Imagine, France)
2. Conventional ultrasound examination: including grayscale ultrasound images, CDFI images, and Angio PLUS (AP) image acquisition.
Sponsors
Fifth Affiliated Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Non-pregnant women aged 18 years or older; 2. Histopathologically confirmed invasive breast cancer; 3. Receiving neoadjuvant therapy as part of their treatment regimen; 4. Completion of a multimodal ultrasound examination before surgery after standard neoadjuvant therapy.
Exclusion criteria
Exclusion criteria: 1.Lesions that cannot be fully visualized in a single ultrasound section (maximum lesion diameter >5 cm); 2.Patients who have previously received other breast radiotherapy, surgery, or drug treatment; 3.Lack of complete clinical and pathological data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathological Complete Response (pCR) after neoadjuvant therapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Breast-Conserving Surgery Rate (BCS Rate); | — |
Countries
China
Contacts
Public ContactWen Xin
Fifth Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed