perinatal depression
Conditions
Interventions
intervention group:Internet-based cognitive behavior therapy
control group:health education+treatment as usual
Sponsors
The Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. PND group: a) Diagnosed and evaluated using the Structured Clinical Interview for DSM-5 Disorders (SCID-5), meeting the criteria for current major depressive episode; b) HAMD-17 >= 14 points and YMRS = 28 weeks) or within 1 year postpartum; e) Han ethnicity, able to understand and communicate in the language required for the study; f) Voluntarily participate in the study and sign a written informed consent form. 2. High-risk group: a) Edinburgh Postnatal Depression Scale score between 9 and 13 (exclusive), and not meeting the SCID criteria for current major depressive episode; b) Meeting any one of the following: history of perinatal/non-perinatal depression or anxiety; history of pregnancy complications or adverse pregnancy outcomes; discontinuation of antidepressants within the past year; history of childhood abuse; or high-risk pregnant women predicted by the onset prediction model; c) Aged 18-45 years; d) Currently in pregnancy (gestational age = 28 weeks) or within 1 year postpartum; e) Han ethnicity, able to understand and communicate in the language required for the study; f) Voluntarily participate in the study and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: a) Current or past history of schizophrenia, bipolar disorder, etc. (anxiety disorder spectrum is not excluded); b) History of neurological diseases or major physical illnesses (such as thyroid disease, lupus erythematosus, diabetes, lung, liver or kidney damage, infections, major trauma, glaucoma, etc.); or history of substance use disorders; c) Patients with clear current suicide plans and/or suicide attempts; d) Other conditions that researchers believe may affect the implementation of the study (such as color blindness, hearing impairment, intellectual disability, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction rate of Hamilton Depression Rating Scale (HAMD);Remission rate of Hamilton Depression Rating Scale (HAMD);Reduction rate of Hamilton Anxiety Rating Scale (HAMA);Remission rate of Hamilton Anxiety Rating Scale (HAMA); | — |
Secondary
| Measure | Time frame |
|---|---|
| HAMD scoring;HAMA scoring;GAD-7 Score;PHQ-9 Score;EPDS Score;PSS Score;PSQI Score;PDQ-D Score;GSRS Score;RRS Score;CD-RISC Score;CTQ Score;DAS Score;BFQ Score;FAD Score;Dietary Habits Questionnaire;cognitive; | — |
Countries
China
Contacts
Public ContactYan Zhang
The Second Xiangya Hospital of Central South University
Outcome results
None listed