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Clinical application of fully enclosed pulse positive pressure vortex module flush-seal tube system in reducing the incidence of central line-related bloodstream infections (CRBSI) in deep vein catheterization and midline catheterization

Clinical application of fully enclosed pulse positive pressure vortex module flush-seal tube system in reducing the incidence of central line-related bloodstream infections (CRBSI) in deep vein catheterization and midline catheterization

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121675
Enrollment
Unknown
Registered
2026-04-01
Start date
2026-04-06
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Experimental group:The fully enclosed pulse positive pressure vortex device flushing and sealing tube system, featuring a pre-filled integrated sterile structure, is connected to a three-way connector
Control group:The traditional A-C-L catheter maintenance process is adopted, which involves assessment, pulse cleaning, and positive pressure locking. Each maintenance process is manually completed by

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Hospitalized patients aged 18 and above with severe conditions who require deep venous catheterization or central line catheter therapy; 2. Expected indwelling catheter time >=7 days; 3. The catheterization site and procedure comply with aseptic technique standards; 4. Those who have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with clear signs of infection or positive blood cultures before catheterization; 2. Combined with severe immunosuppression (such as active tumor chemotherapy, long-term hormone use, organ transplantation, etc.); 3. Non-standard use of catheters or poor patient compliance; 4. Combined bleeding tendency or coagulation mechanism disorder.

Design outcomes

Primary

MeasureTime frame
Incidence of catheter-related infections;

Secondary

MeasureTime frame
Closedness and anti-reflux capability of the flushing and locking system;

Countries

China

Contacts

Public ContactLi Lianchi

West China Hospital, Sichuan University

13880247512@163.com+86 138 8024 7512

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026