Psoriasis
Conditions
Interventions
Compound Qingdai Capsule intervention group:Compound Qingdai Capsules, 4 capsules each time, 3 times a day.
Blank control group:Observe patient symptoms only, without intervention
Sponsors
Gong An County People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-70 years (inclusive), no gender restriction; 2. Clinically diagnosed with moderate to severe plaque psoriasis, with severity defined according to the "Chinese Psoriasis Diagnosis and Treatment Guidelines (2023 Edition)": PASI = 3, BSA = 3%, or DLQI = 6; 3. No clinically significant active infection; 4. No systemic treatment in the past 2 months; 5. Willing to follow medical advice and take medication regularly for at least 12 weeks, attend regular follow-ups, and have complete clinical basic information and medical records.
Exclusion criteria
Exclusion criteria: 1.Patients with active tuberculosis, active hepatitis B virus infection, human immunodeficiency virus (HIV) infection, severe bacterial infections, or other severely immunocompromised conditions; patients with concurrent severe diseases of vital organs and tissues (e.g., heart, brain, lungs, liver, kidneys); patients with severe hepatic or renal impairment; or patients with concurrent malignancies; 2. Female patients who are pregnant, breastfeeding, or planning to become pregnant in the near future; 3.Patients allergic to or intolerant of Compound Qingdai Capsules; 4.Other conditions that, in the opinion of the investigator, make the patient unsuitable to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Psoriasis Area and Severity Index (PASI) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Affected body surface area (BSA);Physician Global Assessment (PGA);Dermatology Life Quality Index (DLQI);Scalp Psoriasis Severity Index (PSSI);Modified Nail Psoriasis Severity Index (mNAPSI);Static Physician’s Global Assessment of Genitalia (sPGA-G);Weight;Blood Pressure;Waist circumference; | — |
Countries
China
Contacts
Public ContactJinfang Chen
Gong An County People's Hospital
Outcome results
None listed