Thyroid cancer
Conditions
Interventions
Index test:68Ga-Trop2 PET/CT
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Aged >=18, male or female; (2) Patients with newly diagnosed papillary thyroid cancer or patients with elevated thyroid globulin after total thyroidectomy/I-131 treatment: a) Patients with newly diagnosed papillary thyroid cancer who have been confirmed by pathological examination and have not received any treatment; or b) Patients with elevated serum Tg (>=1 ng/mL) after total thyroidectomy for previous papillary thyroid cancer or after iodine treatment for papillary thyroid cancer; (3) Patients with an estimated survival time of >3 months as determined by the doctor; (4) Patients who voluntarily sign the informed consent form; (5) Patients who are willing and able to follow the study protocol.
Exclusion criteria
Exclusion criteria: (1) Those who cannot tolerate intravenous administration (such as history of fainting from acupuncture or blood); (2) Those who, in the opinion of the researcher, are not suitable for or unable to complete imaging examinations such as PET due to special reasons, including claustrophobia, radiophobia, etc.; (3) Practitioners who need to be exposed to radioactive conditions for a long time; (4) Those with severe diseases of the heart, kidney, lung, blood vessels, nerves, nervous system, immune deficiency diseases, and hepatitis/cirrhosis; (5) Those with other conditions that, in the opinion of the researcher, make them unsuitable for participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax (Standardized Uptake Value max);sensitivity;specificity;accuracy; | — |
Countries
China
Contacts
Public ContactShaoli Song
Fudan University Shanghai Cancer Center
Outcome results
None listed