None
Conditions
Interventions
EOIB group:Perform bilateral intercostal block of the external oblique muscles between the midline of the clavicle and the anterior axillary line on the 6th rib, with 20 ml of 0.4% ropivacaine on each
TAPB group:Undergoing ultrasound-guided transversus abdominis muscle plane block, performed below the rib margin, with 20 ml of 0.4% ropivacaine on each side
Sponsors
Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. ASA grades I-III; 2. Age range: 18-70 years old; 3.BMI 18.5~30 kg/m^2; 4. Selective laparoscopic liver resection; 5. The informed consent form has been signed.
Exclusion criteria
Exclusion criteria: 1. Daily use of opioid analgesics or history of opioid abuse; 2. The situation where nerve block cannot be performed, such as skin infection at the puncture site; 3. Allergic to any of the drugs used in the study, or with a history of allergies; 4. Having cognitive impairment, mental or neurological disorders, motor or sensory deficits, and inability to cooperate; 5. Severe coagulation dysfunction; 6. Severe kidney, liver, lung, or heart dysfunction; 7. Participated in other clinical trials within the 3 months prior to enrollment in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative area under the curve at rest 24 hours after surgery Visual Analog Scale AUC VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| AUC VAS at rest and cough at 1 h, 2 h, 4 h, and 8 h postoperatively;VAS scores at rest and cough state at 1 h, 2 h, 4 h, 8 h, and 24 h postoperatively;The frequency of salvage analgesia, cumulative opioid dosage, and adverse reactions at 1 h, 2 h, 4 h, 8 h, and 24 h after surgery;Preoperative and postoperative liver and kidney function on days 1 and 3;Preoperative and postoperative day 1 neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and lymphocyte/monocyte ratio, etc;QoR-15 scores before and 1 day after surgery;Postoperative retention time of abdominal drainage tube, length of hospital stay, etc; | — |
Countries
China
Contacts
Public ContactYi Zhang
Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed