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A Clinical Evaluation of the Safety and Efficacy of Ciprofol in Combination with Alfentanil for Anesthesia During Ureteroscopic Holmium Laser Lithotripsy

A Clinical Evaluation of the Safety and Efficacy of Ciprofol in Combination with Alfentanil for Anesthesia During Ureteroscopic Holmium Laser Lithotripsy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121646
Enrollment
Unknown
Registered
2026-04-01
Start date
2025-10-03
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ureteral calculi

Interventions

Ciprofol Group:Anesthesia Induction: Ciprofol + Alfentanil
Maintenance: Ciprofol + Alfentanil (with dose adjustments as clinically indicated).
Propofol Group:Anesthesia Induction: Propofol + Alfentanil
Maintenance: Propofol + Alfentanil (with dose adjustments as clinically indicated).

Sponsors

Zhongshan Torch Hi-tech Industrial Development Zone People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Assessed by the Department of Urology as requiring ureteroscopic lithotripsy (URL) treatment; 2) Age between 18 and 65 years, regardless of gender; 3) American Society of Anesthesiologists (ASA) physical status classification of I to III; 4) Body mass index (BMI) between 18.5 and 28 kg/m^2; 5) Absence of severe dysfunction in vital organs such as the heart, liver, or kidneys, and no history of anesthesia drug allergy; 6) Signed written informed consent form, with full understanding of the study-related information.

Exclusion criteria

Exclusion criteria: 1) Severe cardiovascular diseases (e.g., uncontrolled hypertension, severe arrhythmia); 2) Hepatic or renal insufficiency; 3) Coagulation disorders; 4) History of psychiatric disorders or inability to cooperate with pain assessment; 5) Pregnancy or lactation; 6) Inability to complete study follow-up or data collection due to other reasons.

Design outcomes

Primary

MeasureTime frame
Intraoperative Blood Pressure;Intraoperative Hemodynamics;Injection Pain;

Countries

China

Contacts

Public ContactYuan Bo

Zhongshan Torch Hi-tech Industrial Development Zone People's Hospital

13902824129@163.com+86 139 0282 4129

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026