sensitive skin
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Healthy females or males aged between 18 and 60 years old. 2.Those who test positive in the lactic acid stinging test. 3.Individuals with sensitive, reddish, and dry facial skin. 4.Those who have good compliance with this project and possess good communication skills. 5.Those who are willing to undergo follow-up and relevant non-invasive tests. 6.Those who can understand the experimental process, voluntarily participate in the experiment, and sign the written informed consent form.
Exclusion criteria
Exclusion criteria: 1.Those who have applied any topical medications to the tested area within the past two months. 2.Those who have taken antihistamines within the past week or immunosuppressants within the past month. 3.Those with inflammatory skin diseases that have not clinically healed. 4.Patients with insulin-dependent diabetes mellitus. 5.Patients with asthma or other chronic respiratory diseases who are currently receiving treatment. 6.Those who have received anti-cancer chemotherapy within the past six months. 7.Patients with immunodeficiency or autoimmune diseases. 8.Women who are planning to become pregnant, are pregnant, or are breastfeeding. 9.Those who have obvious scars, pigmentation, atrophy, nevus flammeus, sunburns, wounds, abrasions, tattoos, or other defects at or near the skin test site, which may affect the determination of the test results. 10.Those who have received medical aesthetic treatments such as intense pulsed light skin rejuvenation, laser treatments, or other facial cosmetic procedures that may affect the skin condition within the past three months. 11.Those who have participated in similar facial tests, oral medication tests, or other clinical trials within the past two months. 12.Those with a high degree of physical sensitivity, and those who are known to be allergic to ingredients in cosmetics or daily chemical products, alcohol, rubber, or medications, etc. 13.Those who need to be exposed to outdoor sunlight for a long time due to work or other reasons. 14.Those with other iatrogenic problems that may affect the test results (such as a history of coagulation disorders, severe hyperglycemia, hypertension, hyperlipidemia, mental diseases, or other major diseases). 15.Those who are considered unsuitable for participating in the trial according to other clinical evaluations. 16.Those who do not volunteer to participate or cannot complete the specified test content as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transepidermal water loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| VISIA CR red zone a* value;Lactic Acid Sting Test;Water content of the stratum corneum of the skin;Safety index; | — |
Countries
China
Contacts
Dematology Hospital of Southern Medical University